Determining the effectiveness of increased SMCHD1 expression to suppress DUX4 in FSHD muscle cells and model mice
There are two genetic types of FSHD: FSHD1 and FSHD2. FSHD1 (representing around 95% of FSHD cases) is associated with a loss of repetitive DNA units called D4Z4 on the end of…Read More
Investigation DUX4 activity during development of hESC-derived skeletal muscle.
In 2011, FSHD Global funded Genea Biocells to isolate the first embryonic stem cells from patients with FSHD. Genea has done an excellent job developing these lines, and sharing them…Read More