About FSHD Canada Foundation
Funded Research

In vivo model to validate drugs targeting DUX4 enhancer/promoter activity

Principle Investigator: Yosuke Hiramuki (at Peter Jone’s laboratory) Research Institution: University of Nevada DUX4 is normally expressed in testis in healthy individuals and aberrantly expressed in specific skeletal muscles of…

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Pre-clinical testing for FSHD CRISPR-inhibition therapy

Principle Investigator: Associate Professor Peter Jones Research Institution: University of Nevada CRISPR technology provides an avenue for targeting and correcting virtually any sequence in the human genome, with long-term or…

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Facio Therapies

Facio Therapies, established in 2014, is a Netherlands-based company with a single focus – to overcome FSHD by developing a causal therapy that restores the natural repression of muscle-toxic DUX4.…

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Development of next-generation AAV vectors for effective CRISPR inhibition of FSHD

Investigator: Charis L. Himeda, PhD, Research Assistant Professor, University of Nevada, Reno School of Medicine, Reno NV USA CRISPR technology provides an avenue for specifically targeting and manipulating virtually any…

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Identify Biomarkers for FSHD Using Omics Approaches

Investigator: Yi-Wen Chen, Ph.D. (Children’s Research Institute in Silver Spring, Maryland) Biomarkers are biological changes that can be used as indicators of physiological and disease states. Biomarkers can be valuable…

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Stryka-001 treatment in the FSHD-like mouse model

Investigator: Dean Burkin, PhD, and Peter Jones, PhD (University of Nevada, Reno School of Medicine) This is a project to validate the efficacy of a potential drug therapy for FSHD…

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